|
| |
|
|
|
|
| |
|
|
| |
The
Neurologic AIDS Research Consortium (NARC) is supported by the National
Institutes of Health to design and carry out clinical trials to improve the
therapy for HIV induced neurologic disease, and neurologic conditions
associated with the AIDS virus. This consortium was established in 1993 when
the NARC grant submitted by David B. Clifford, M.D. of Washington University
School of Medicine was funded by the National Institute of Neurologic Disorders
and Stroke (NINDS) to establish the consortium. Since that time the grant has
supported studies of the natural history of neurologic performance in advanced
AIDS, treatment of HIV associated peripheral neuropathy, progressive multifocal
leukoencephalopathy, and cytomegalovirus.
|
|
| |
|
|
|
|
| |
Persons interested in treatment for neurologic HIV complications should contact
a NARC site near their home, or may contact the NARC coordinating center at
:314-747-8426, NARC Coordinator, Mary Gould
|
|
|
|
| |
The NARC primarily sponsors studies in conjunction with the AIDS Clinical
Trials Group (ACTG) . The complications of HIV are dynamically evolving over
time. In general neurologic complications typically occurring in advanced
disease states are increasing in incidence even while some of the early
complications associated with AIDS are less commonly encountered due to
improved preventive therapy. The impact of the new generation of antiretroviral
drugs, and the impact of predominantly multidrug therapy remain to be seen.
Several of the key new drugs fail to penetrate the brain, thus making it
possible that the incidence of neurologic disease may continue to increase. The
Neurologic AIDS Research Consortium is designed to continue to develop studies
based on the current challenges of the AIDS epidemic. For information regarding
neurologic studies, investigators at regional centers participating in the
Neurologic AIDS Research Consortium may be contacted, or the NARC coordinating
center may be contacted directly.
|
|
|
|
| |
Neurologic AIDS Research Consortium
David B. Clifford , MD - Principal Investigator
Phone (314) 747-8423, Fax (314) 747-8427
|
|